Article
Teashirt is required for transcriptional repression mediated by high Wingless levels.
The EMBO journal - 15 Jan 2001
Waltzer L, Vandel L, Bienz M
Abstract excerpt
During development, extracellular signals often act at multiple thresholds to specify distinct transcriptional and cellular responses. For example, in the embryonic midgut of Drosophila, low Wingless levels stimulate the transcription of homeotic genes whereas high Wingless levels repress these genes. Wingless- mediated transcriptional activation is conferred by Drosophila: T-cell factor (dTCF) and its...
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