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Article

Cerebrospinal fluid levels of phosphorylated tau and Aβ1-38/Aβ1-40/Aβ1-42 in Alzheimer's disease with PS1 mutations.

Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis - 1 Jun 2013

Ikeda Masaki, Yonemura Kimie, Kakuda Satoko, Tashiro Yuichi, Fujita Yukio, Takai Eriko, Hashimoto Yukiko, Makioka Kouki, Furuta Natsumi, Ishiguro Koichi, Maruki Risa, Yoshida Jun'ichi, Miyaguchi Osamu, Tsukie Tamao, Kuwano Ryouzou, Yamazaki Tsuneo, Yamaguchi Haruyasu, Amari Masakuni, Takatama Masamitsu, Harigaya Yasuo, Okamoto Koichi

Abstract excerpt

We studied seven cases of Alzheimer's disease (AD). Six of the patients had presenilin 1 (PS1) mutations (PS1AD). Three novel PS1 mutations (T99A, H131R and L219R) and three other missense mutations (M233L, H163R and V272A) were found in the PS1AD group. We measured the levels of phosphorylated t...

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Identifiers

PMID: 23638752
DOI: 10.3109/13506129.2013.790810

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23638752-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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