Article
Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease.
Brain pathology (Zurich, Switzerland) - 1 Jul 2011
Sepulveda-Falla Diego, Matschke Jakob, Bernreuther Christian, Hagel Christian, Puig Berta, Villegas Andres, Garcia Gloria, Zea Julian, Gomez-Mancilla Baltazar, Ferrer Isidre, Lopera Francisco, Glatzel Markus
Abstract excerpt
Early-onset familial Alzheimer's disease (AD) caused by presenilin-1 mutation E280A (PS1-E280A) presents wide clinical and neuropathological variabilities. We characterized clinically and neuropathologically PS1-E280A focusing in cerebellar involvement and compared it with early-onset sporadic Al...
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