Article
Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias.
Dementia and geriatric cognitive disorders - 1 Jan 2011
Bibl Mirko, Mollenhauer Brit, Lewczuk Piotr, Esselmann Hermann, Wolf Stefanie, Otto Markus, Kornhuber Johannes, Rüther Eckart, Wiltfang Jens
Abstract excerpt
BACKGROUND/AIMS: We determined cerebrospinal fluid (CSF) concentrations of amyloid-β (Aβ)(1-38), Aβ(1-40), Aβ(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25) and primary progressive aphasia (PPA, n = 12) as compared to Alzheimer's dementia (AD, n = 25) and nondemented controls (n = 20). METHODS: Commercially available ELISA and...
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