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Article

Complex genetic architecture of cardiac disease in a wild type inbred strain of Drosophila melanogaster.

PloS one - 1 Jan 2013

Zhang Zhi, Hsieh Benjamin, Poe Amy, Anderson Julie, Ocorr Karen, Gibson Greg, Bodmer Rolf

Abstract excerpt

Natural populations of the fruit fly, Drosophila melanogaster, segregate genetic variation that leads to cardiac disease phenotypes. One nearly isogenic line from a North Carolina peach orchard, WE70, is shown to harbor two genetically distinct heart phenotypes: elevated incidence of arrhythmias, and a dramatically constricted heart diameter in both diastole and systole, with resemblance to restrictive...

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Identifiers

PMID: 23638165
DOI: 10.1371/journal.pone.0062909
PMCID: PMC3639251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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