Article

<i>Drosophila</i> Modeling Identifies Increased Sleep as a Link Between Insomnia and Cardiovascular Disease

2025-04-09

Abstract excerpt

Insomnia is a common sleep disorder associated with negative long-term health outcomes. Mendelian randomization studies have found that insomnia significantly increases the risk of cardiovascular disease (CVD). To better understand the link between sleep and heart health, we identify genes associated with both insomnia and CVD. We model the disruption of the Drosophila melanogaster orthologs in neurons and cardiac...

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Literature Corpus work: f870a8cf-dc6a-53fd-937a-89e0c1b6ceac
DOI: 10.1101/2025.04.07.647668

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