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Article

Genetic variation for cardiac dysfunction in Drosophila.

PloS one - 11 Jul 2007

Ocorr Karen A, Crawley Timothy, Gibson Greg, Bodmer Rolf

Abstract excerpt

BACKGROUND: Common diseases may be attributed to combinations of variant alleles, but there are few model systems where the interactions among such variants can be studied in controlled genetic crosses. While association studies are designed to detect common polymorphisms of moderate effect, new approaches are required to characterize the impact on disease of interactions among rare alleles. METHODOLOGY/PRINCIPAL...

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Identifiers

PMID: 17622346
DOI: 10.1371/journal.pone.0000601
PMCID: PMC1913553

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Source receipt: pubmed, retrieved 7 Sept 2026.

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