Article
Association between ZIC2, RASGRF1, and SHISA6 genes and high myopia in Japanese subjects.
Investigative ophthalmology & visual science - 13 Nov 2013
Oishi Maho, Yamashiro Kenji, Miyake Masahiro, Akagi-Kurashige Yumiko, Kumagai Kyoko, Nakata Isao, Nakanishi Hideo, Yoshikawa Munemitsu, Oishi Akio, Gotoh Norimoto, Tsujikawa Akitaka, Yamada Ryo, Matsuda Fumihiko, Yoshimura Nagahisa
Abstract excerpt
PURPOSE: We investigated the association of genetic variations, which were identified recently in a large-scale genome-wide association study (GWAS) to confer risk of refractive error and common myopia in Caucasians, with high myopia in Japanese subjects. METHODS: The 5 single-nucleotide polymorphisms (SNPs) from the 5 genes TOX, RDH5, ZIC2, RASGRF1, and SHISA6, were genotyped in 1339 unrelated highly myopic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.