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Article

Inactivation of the CovR/S virulence regulator impairs infection in an improved murine model of Streptococcus pyogenes naso-pharyngeal infection.

PloS one - 1 Jan 2013

Alam Faraz M, Turner Claire E, Smith Ken, Wiles Siouxsie, Sriskandan Shiranee

Abstract excerpt

Streptococcus pyogenes is a leading cause of pharyngeal infection, with an estimated 616 million cases per year. The human nasopharynx represents the major reservoir for all S. pyogenes infection, including severe invasive disease. To investigate bacterial and host factors that influence S. pyoge...

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Identifiers

PMID: 23637876
DOI: 10.1371/journal.pone.0061655
PMCID: PMC3636223

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23637876-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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