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Article

Pseudomonas aeruginosa tssC1 links type VI secretion and biofilm-specific antibiotic resistance.

Journal of bacteriology - 1 Oct 2011

Zhang Li, Hinz Aaron J, Nadeau Jean-Paul, Mah Thien-Fah

Abstract excerpt

Biofilm-specific antibiotic resistance is influenced by multiple factors. We demonstrated that Pseudomonas aeruginosa tssC1, a gene implicated in type VI secretion (T6S), is important for resistance of biofilms to a subset of antibiotics. We showed that tssC1 expression is induced in biofilms and confirmed that tssC1 is required for T6S.

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Identifiers

PMID: 21784934
DOI: 10.1128/JB.00268-11
PMCID: PMC3187457

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