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Article

Investigating the link between imipenem resistance and biofilm formation by Pseudomonas aeruginosa.

Microbial ecology - 1 Jul 2014

Musafer Hadeel K, Kuchma Sherry L, Naimie Amanda A, Schwartzman Joseph D, Al-Mathkhury Harith J Fahad, O'Toole George A

Abstract excerpt

Pseudomonas aeruginosa, a ubiquitous environmental organism, is a difficult-to-treat opportunistic pathogen due to its broad-spectrum antibiotic resistance and its ability to form biofilms. In this study, we investigate the link between resistance to a clinically important antibiotic, imipenem, and biofilm formation. First, we observed that the laboratory strain P. aeruginosa PAO1 carrying a mutation in the oprD...

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Identifiers

PMID: 24435545
DOI: 10.1007/s00248-013-0361-6
PMCID: PMC8978818

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