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Article

The serine phosphatase SerB of Porphyromonas gingivalis suppresses IL-8 production by dephosphorylation of NF-κB RelA/p65.

PLoS pathogens - 1 Jan 2013

Takeuchi Hiroki, Hirano Takanori, Whitmore Sarah E, Morisaki Ichijiro, Amano Atsuo, Lamont Richard J

Abstract excerpt

Porphyromonas gingivalis is a major pathogen in severe and chronic manifestations of periodontal disease, which is one of the most common infections of humans. A central feature of P. gingivalis pathogenicity is dysregulation of innate immunity at the gingival epithelial interface, including supp...

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Identifiers

PMID: 23637609
DOI: 10.1371/journal.ppat.1003326
PMCID: PMC3630210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23637609-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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