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Article

Role of Porphyromonas gingivalis SerB in gingival epithelial cell cytoskeletal remodeling and cytokine production.

Infection and immunity - 1 Jun 2008

Hasegawa Yoshiaki, Tribble Gena D, Baker Henry V, Mans Jeffrey J, Handfield Martin, Lamont Richard J

Abstract excerpt

The SerB protein of Porphyromonas gingivalis is a HAD family serine phosphatase that plays a critical role in entry and survival of the organism in gingival epithelial cells. SerB is secreted by P. gingivalis upon contact with epithelial cells. Here it is shown by microarray analysis that SerB impacts the transcriptional profile of gingival epithelial cells, with pathways involving the actin cytoskeleton and...

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Identifiers

PMID: 18391005
DOI: 10.1128/IAI.00156-08
PMCID: PMC2423092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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