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Article

Association of MDM2 SNP309 and TP53 Arg72Pro polymorphisms with risk of endometrial cancer.

Oncology reports - 1 Jul 2013

Yoneda Tomoko, Kuboyama Ayumi, Kato Kiyoko, Ohgami Tatsuhiro, Okamoto Kanako, Saito Toshiaki, Wake Norio

Abstract excerpt

The incidence of endometrial cancer, a common gynecological malignancy, is increasing in Japan. We have previously shown that the ER/MDM2/p53/p21 pathway plays an important role in endometrial carcinogenesis. In the present study, we investigated the effects of germline single nucleotide polymorphisms in murine double minute 2 (MDM2) SNP309, TP53 Arg72Pro, ESR1 PvuII and XbaI, and p21 codon 31 on endometrial...

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Source

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Identifiers

PMID: 23624782
DOI: 10.3892/or.2013.2433
PMCID: PMC3729233

Genes

MDM2
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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