Article
Toll-like receptor 2 polymorphisms and their effect on the immune response to ESAT-6, Pam3CSK4 TLR2 agonist in pulmonary tuberculosis patients and household contacts.
Cytokine - 1 Feb 2020
Mandala Jyothi Priya, Ahmad Shazia, Pullagurla Ashwini, Thada Shruthi, Joshi Lavanya, Ansari Mohd Soheb Sadat, Valluri Vijaya Lakshmi, Gaddam Suman Latha
Abstract excerpt
Toll-like receptors (TLRs) play a pivotal role in organizing the effective immune response through inducing the pro-inflammatory cytokines for control of tuberculosis infection and TLR polymorphisms are associated with altered cytokine levels have been described. Therefore, the main aim of the present study was to confirm whether TLR2 (C2029T, G2258A) polymorphisms effects the cytokine production in PTB patients...
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