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Article

Genetic association of G896A polymorphism of TLR4 gene in leprosy through family-based and case-control study designs.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Dec 2013

Suryadevara Naveen Chandra, Neela Venkata Sanjeev Kumar, Kovvali Srinivas, Pydi Satya Sudheer, Jain Suman, Siva Sai K S R, Valluri Vijaya Lakshmi, Spurgeon Anandaraj M P J

Abstract excerpt

BACKGROUND: Polymorphisms in TLR4 may change the function of the protein and alter the efficiency of immune response of host to infection. The high relevance of host gene polymorphisms with outcome of Mycobacterium leprae infection led us to study the genetic association of TLR4 G896A polymorphism in order to identify its risk among contacts of affected leprosy patients. METHODS: For case-control study design a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24169261
DOI: 10.1093/trstmh/trt084

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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