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Article

In non-small cell lung cancer mitogenic signaling leaves Sprouty1 protein levels unaffected.

Cell biochemistry and function - 1 Jan 2014

Kral Rosana Maria, Mayer Christoph-Erik, Vanas Vanita, Gsur Andrea, Sutterlüty-Fall Hedwig

Abstract excerpt

Sprouty1 protein belongs to a family of receptor tyrosine kinase-mediated signaling inhibitors, whose members are usually regulated by growth factors to form a negative feedback loop. Correspondingly fluctuations of Sprouty1 mRNA in response to single growth factors have been observed. In this report, we investigate Sprouty1 protein levels and show that in non-small cell lung carcinoma-derived cells, the...

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PMID: 23616430
DOI: 10.1002/cbf.2976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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