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Article

Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection.

PloS one - 1 Jan 2013

Chang Chia Lin, Semyonov Jenia, Cheng Po Jen, Huang Shang Yu, Park Jae Il, Tsai Huai-Jen, Lin Cheng-Yung, Grützner Frank, Soong Yung Kuei, Cai James J, Hsu Sheau Yu Teddy

Abstract excerpt

In mammals, carcinoembryonic antigen cell adhesion molecules (CEACAMs) and pregnancy-specific glycoproteins (PSGs) play important roles in the regulation of pathogen transmission, tumorigenesis, insulin signaling turnover, and fetal-maternal interactions. However, how these genes evolved and to what extent they diverged in humans remain to be investigated specifically. Based on syntenic mapping of chordate...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 23613906
DOI: 10.1371/journal.pone.0061701
PMCID: PMC3628338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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