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Carcinoembryonic antigen gene family: Molecular biology and clinical perspectives

1 Jan 1991

Abstract excerpt

The carcinoembryonic antigen (CEA) gene family belongs to the immunoglobulin super-gene family and can be divided into two main subgroups based on sequence comparisons. In humans it is clustered on the long arm of chromosome 19 and consists of approximately 20 genes. The CEA subgroup genes code for CEA and its classical crossreacting antigens, which are mainly membrane-bound, whereas the other subgroup genes...

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PMID: 1941355
DOI: 10.1002/jcla.1860050510

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