Article
Association of brain serotonin transporter availability and brain-derived neurotrophic factor in models of serotonin transporter genotypes in healthy subjects.
Journal of clinical psychopharmacology - 1 Jun 2013
Chou Yuan-Hwa, Chen Chih-Ken, Wang Shyh-Jen, Tsai Shih-Jen, Lirng Jiing-Feng, Liou Ying-Jay, Lin Chun-Lung, Yang Kai-Chun, Lin Ming-Wei, Lo Whai-Chin, Liao Mei-Hsiu, Chen Chia-Chieh
Abstract excerpt
The S-allele of functional polymorphisms of the serotonin transporter (SERT) gene has been demonstrated to have lower transcriptional activity compared with the L-allele, which shows low expression of SERT in the brain. However, this finding cannot be consistently replicated in vivo. The aim of t...
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