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Article

The Serotonin Transporter Gene Polymorphisms and Risk of Ischemic Stroke.

Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2018

Mortensen Janne Kaergaard, Kraglund Kristian Lundsgaard, Johnsen Søren Paaske, Mors Ole, Andersen Grethe, Buttenschøn Henriette N

Abstract excerpt

INTRODUCTION: Serotonin is known as a neurotransmitter; however, it also plays an important role in platelet aggregation as it is released upon platelet activation. The serotonin transporter (SERT) is responsible for the uptake of serotonin into platelets. Functional polymorphisms in the SERT gene may influence platelet activity, as they result in different levels of transporters and thereby different levels of...

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PMID: 29614501
DOI: 10.1159/000488364

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SLA

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