Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Positive regulation of osteogenesis by bile acid through FXR.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2013

Cho Sun Wook, An Jee Hyun, Park Hyojung, Yang Jae-Yeon, Choi Hyung Jin, Kim Sang Wan, Park Young Joo, Kim Seong Yeon, Yim Mijung, Baek Wook-Young, Kim Jung-Eun, Shin Chan Soo

Abstract excerpt

Farnesoid X receptor (FXR) is a nuclear receptor that functions as a bile acid sensor controlling bile acid homeostasis. We investigated the role of FXR in regulating bone metabolism. We identified the expression of FXR in calvaria and bone marrow cells, which gradually increased during osteoblas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Acids and Salts
Share to Bone Resorption

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organ Size

Share to Osteoblasts

Share to Osteoclasts

Share to Osteogenesis

Share to Ovariectomy

Share to Receptors, Cytoplasmic and Nuclear

Source

Identifiers

PMID: 23609136
DOI: 10.1002/jbmr.1961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23609136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Positive regulation of osteogenesis by bile acid through FXR.PMID 23609136Read ↗

The role of retinoic acid receptor-related orphan receptors in skeletal diseasesSemantic proximity Read ↗

A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism.Semantic proximity Read ↗

Modeling hepatic osteodystrophy in Abcb4 deficient mice.Semantic proximity Read ↗

Raised Hepatic Bile Acid Concentrations During Pregnancy in Mice Are Associated with Reduced Farnesoid X Receptor FunctionSemantic proximity Read ↗

β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice.Semantic proximity Read ↗

Osteoblast-targeted overexpression of PPARγ inhibited bone mass gain in male mice and accelerated ovariectomy-induced bone loss in female mice.Semantic proximity Read ↗

PPARβ/δ governs Wnt signaling and bone turnover.Semantic proximity Read ↗

Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts.Semantic proximity Read ↗

Up-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis in Gja1Jrt/+ stromal cell cultures.Semantic proximity Read ↗

Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton.Semantic proximity Read ↗

Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone.Semantic proximity Read ↗

Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.