Article
β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice.
Endocrinology - 1 Jan 2018
Frey Julie L, Kim Soohyun P, Li Zhu, Wolfgang Michael J, Riddle Ryan C
Abstract excerpt
Wnt-initiated signaling through a frizzled receptor and the low-density lipoprotein-related receptor-5 coreceptor instructs key anabolic events during skeletal development, homeostasis, and repair. Recent studies indicate that Wnt signaling also regulates the intermediary metabolism of osteoblastic cells, inducing glucose consumption in osteoprogenitors and fatty acid utilization in mature osteoblasts. In this...
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