Article
The role of HLA DQ2 and DQ8 in dissecting celiac-like disease in common variable immunodeficiency.
Journal of clinical immunology - 1 Jul 2013
Venhoff Nils, Emmerich Florian, Neagu Michaela, Salzer Ulrich, Koehn Corinna, Driever Sibyll, Kreisel Wolfgang, Rizzi Marta, Effelsberg Nora M, Kollert Florian, Goldacker Sigune, Voll Reinhard E, Warnatz Klaus, Thiel Jens
Abstract excerpt
OBJECTIVES: Gastrointestinal manifestations are frequent in patients with common variable immunodeficiency (CVID), and some of the patients present with celiac-like features. Diagnosing celiac disease (CD) in CVID however is challenging, as autoantibody detection and histopathology of the small intestine cannot reliably discriminate between classic CD and a celiac-like disease in these individuals. For the...
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