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Tuning the replication fork progression by the initiation frequency.

Environmental microbiology - 1 Dec 2013

González Moreno Sara, Mata Martín Carmen, Ferrera Guillén Encarna, Guzmán Elena C

Abstract excerpt

The thermo-resistant period of the thermo-sensitive ribonucleotide reductase RNR101 encoded by the nrdA101 allele in Escherichia coli is prolonged for 50 min at 42°C, enabling an increase in DNA content of about 45%. Assuming that fork progression in the nrdA101 mutant is impaired, the question whether reduced number of ongoing replication rounds altered the thermo-resistant period in this strain was...

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Identifiers

PMID: 23607621
DOI: 10.1111/1462-2920.12127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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