Article

<i>In Vitro</i> Validation of Computationally Predicted Oncogenic Driver Mutations in EGFR Tyrosine Kinase Domain

2023-01-31

Abstract excerpt

Epidermal Growth Factor Receptor (EGFR) signaling is known to play essential roles in growth and development; nevertheless, overexpression and mutation of EGFR have been reported in several cancers. Non-small cell lung cancer (NSCLC), the most observed type of lung cancer, harbors the highest number of EGFR tyrosine kinase mutations and therefore, EGFR has become an important therapeutic target for treatment of th...

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Literature Corpus work: 48ad9de0-6d28-5c83-8ec7-36bd0fef1a9b
DOI: 10.1101/2023.01.29.526080

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