Article
Exocrine pancreatic function in hepatocyte nuclear factor 1β-maturity-onset diabetes of the young (HNF1B-MODY) is only moderately reduced: compensatory hypersecretion from a hypoplastic pancreas.
Diabetic medicine : a journal of the British Diabetic Association - 1 Aug 2013
Tjora E, Wathle G, Erchinger F, Engjom T, Molven A, Aksnes L, Haldorsen I S, Dimcevski G, Raeder H, Njølstad P R
Abstract excerpt
OBJECTIVES: To examine the exocrine pancreatic function in carriers of the hepatocyte nuclear factor 1β gene (HNF1B) mutation by direct testing. METHODS: Patients with HNF1B mutations and control subjects were assessed using rapid endoscopic secretin tests and secretin-stimulated magnetic resonance imaging. Seven patients and 25 controls underwent endoscopy, while eight patients and 20 controls had magnetic...
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