Article
The role of pancreatic imaging in monogenic diabetes mellitus.
Nature reviews. Endocrinology - 29 Nov 2011
Haldorsen Ingfrid S, Ræder Helge, Vesterhus Mette, Molven Anders, Njølstad Pål R
Abstract excerpt
In neonatal diabetes mellitus resulting from mutations in EIF2AK3, PTF1A, HNF1B, PDX1 or RFX6, pancreatic aplasia or hypoplasia is typical. In maturity-onset diabetes mellitus of the young (MODY), mutations in HNF1B result in aplasia of pancreatic body and tail, and mutations in CEL lead to lipomatosis. The pancreas is not readily accessible for histopathological investigations and pancreatic imaging might,...
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