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Article

Genetic predisposition to molecular response in patients with myeloproliferative neoplasms treated with hydroxycarbamide.

Leukemia research - 1 Aug 2013

Angona Anna, Bellosillo Beatriz, Alvarez-Larrán Alberto, Martínez-Avilés Luz, Camacho Laura, Pairet Silvia, Fernández-Rodriguez Maria Concepción, Ancochea Agueda, Besses Carles

Abstract excerpt

JAK2V617F allele burden was prospectively measured in polycythemia vera (PV, n=52) and essential thrombocythemia (ET, n=39) patients receiving hydroxycarbamide (HC) and analyzed according to JAK2 46/1 haplotype and genotype of SLC14A1, SLC14A2 and ARG2 urea transporters. Molecular response (MR) was obtained in 68.7% and 38.9% of PV patients with GG and AA or GA genotype in SLC14A2, respectively (p=0.07). No...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23597578
DOI: 10.1016/j.leukres.2013.03.013

Genes

JAK2
ARG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic predisposition to molecular response in patients with myeloproliferative neoplasms treated with hydroxycarbamide.PMID 23597578Read ↗

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