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Article

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis.

Arthritis research & therapy - 18 Apr 2013

Muthuri Stella G, Doherty Sally, Zhang Weiya, Maciewicz Rose A, Muir Kenneth R, Doherty Michael

Abstract excerpt

INTRODUCTION: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA). METHODS: We conducted a case-control study of Caucasian men and women aged 45 to 86 years from Nottingham, United Kingdom (Genetics of OA and Lifestyle (GOAL) study). Cases had clinically severe symptoms and radiographic knee...

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Identifiers

PMID: 23597094
DOI: 10.1186/ar4214
PMCID: PMC4060375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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