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Article

Interaction between angiotensin-converting enzyme gene rs4343 polymorphism, environment factors, and angiotensin II level on susceptibility to knee osteoarthritis.

Reumatologia clinica - 1 Jan 2000

Elnaggar Basma Mohammed Mohammed Ali, Abd Elbaky Nashwa Mohamed, Albeltagy Eman Salah, El Zomor Hala Mohamed

Abstract excerpt

OBJECTIVES: Osteoarthritis (OA) is a complex multifactorial disease. The association of knee OA risk with ACE gene rs4343 polymorphism, gene environment synergistic effect, and angiotensin II serum level has not been previously examined. Therefore, we investigate the ACE gene rs4343 polymorphism in knee OA, and its association with severity of knee OA, and angiotensin II serum level. METHODS: Using a case-control...

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PMID: 39160009
DOI: 10.1016/j.reumae.2024.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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