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Article

Effect of cysteine mutations in the extracellular domain of CM2 on the influenza C virus replication.

PloS one - 1 Jan 2013

Muraki Yasushi, Okuwa Takako, Himeda Toshiki, Hongo Seiji, Ohara Yoshiro

Abstract excerpt

CM2 is the second membrane protein of influenza C virus and possesses three conserved cysteines at residue 1, 6 and 20 in its extracellular domain, all of which are involved in the formation of disulfide-linked oligomers of the molecule. In the present study, to examine the effect of CM2 oligomerization on virus replication, we generated a mutant recombinant virus, rC1620A, in which all three cysteines on CM2...

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Source

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Identifiers

PMID: 23593230
DOI: 10.1371/journal.pone.0060510
PMCID: PMC3617168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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