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Article

Association of L-ficolin levels and FCN2 genotypes with chronic Chagas disease.

PloS one - 1 Jan 2013

Luz Paola R, Boldt Angelica B W, Grisbach Caroline, Kun Jürgen F J, Velavan Thirumalaisamy P, Messias-Reason Iara J T

Abstract excerpt

BACKGROUND: L-ficolin (encoded by FCN2) binds to acetylated sugar moieties of many pathogens, including Trypanosoma cruzi, promoting their phagocytosis and lysis by the complement system. METHODS: We investigated L-ficolin levels in 160 T. cruzi infected patients with chronic Chagas disease and 7...

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Source

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Identifiers

PMID: 23593180
DOI: 10.1371/journal.pone.0060237
PMCID: PMC3617223

Genes

FCN2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23593180-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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