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Article

MASP2 haplotypes are associated with high risk of cardiomyopathy in chronic Chagas disease.

Clinical immunology (Orlando, Fla.) - 1 Jul 2011

Boldt Angelica B W, Luz Paola R, Messias-Reason Iara J T

Abstract excerpt

Mannose-binding lectin (MBL) initiates complement on Trypanosoma cruzi through the MBL-associated serine protease 2 (MASP2). We haplotyped six MASP2 polymorphisms in 208 chronic chagasic patients, being 81 indeterminate and 123 symptomatic (76 with cardiac, 19 with digestive and 28 with cardiodigestive forms) and 300 healthy individuals from Southern Brazil, using PCR with sequence-specific primers. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21489885
DOI: 10.1016/j.clim.2011.03.008

Genes

MASP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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