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Article

Mannose-binding lectin and Toll-like receptor polymorphisms and Chagas disease in Chile.

The American journal of tropical medicine and hygiene - 1 Feb 2012

Weitzel Thomas, Zulantay Inés, Danquah Ina, Hamann Lutz, Schumann Ralf R, Apt Werner, Mockenhaupt Frank P

Abstract excerpt

Mannose-binding lectin (MBL) and Toll-like receptor (TLR) polymorphisms may influence susceptibility and manifestation of Trypanosoma cruzi infection. In northern Chile, we examined 61 asymptomatic patients with chronic Chagas disease (CD), 64 patients with chronic Chagas cardiomyopathy (CCC), and 45 healthy individuals. Low-producer MBL2*B genotypes were more common in CD patients (48%) than healthy individuals...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22302853
DOI: 10.4269/ajtmh.2012.11-0539
PMCID: PMC3269271

Genes

TLR4
MAL
MBL2
TIRAP
TLR1
TLR2
TLR6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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