Article
Association of IL-1B gene polymorphisms with nasopharyngeal carcinoma in a Chinese population.
Clinical oncology (Royal College of Radiologists (Great Britain)) - 1 Apr 2008
Zhu Yinhua, Xu Yongchun, Wei Yesheng, Liang Weibo, Liao Miao, Zhang Lin
Abstract excerpt
AIMS: Interleukin-1beta (IL-1beta) is a multifunctional cytokine that up-regulates the inflammatory response and participates in carcinogenesis, malignant transformation, tumour growth, invasion and metastasis. The IL-1B gene, encoding IL-1beta cytokine, contains several single nucleotide polymorphisms. Previous studies have shown that the polymorphisms of this gene may be associated with an increased risk of...
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