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Article

Early degeneration of photoreceptor synapse in Ccl2/Cx3cr1-deficient mice on Crb1(rd8) background.

Synapse (New York, N.Y.) - 1 Aug 2013

Zhang Jun, Tuo Jingsheng, Cao Xiaoguan, Shen Defen, Li Wei, Chan Chi-Chao

Abstract excerpt

Photoreceptor ribbon synapse releases glutamate to postsynaptic targets. The synaptic ribbon may play multiple roles in ribbon synapse development, synaptic vesicle recycling, and synaptic transmission. Age-related macular degeneration (AMD) patients appear to have fewer or no detectable synaptic ribbons as well as abnormal swelling in the photoreceptor terminals in the macula. However, reports on changes of...

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Identifiers

PMID: 23592324
DOI: 10.1002/syn.21674
PMCID: PMC3745602

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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