Article
BMP4, a strong better prognosis predictor, has a subtype preference and cell development association in gliomas.
Journal of translational medicine - 16 Apr 2013
Bao Zhaoshi, Zhang Chuanbao, Yan Wei, Liu Yanwei, Li Mingyang, Zhang Wei, Jiang Tao
Abstract excerpt
BACKGROUND: The bone morphogenetic family proteins (BMP) are phytogenetically conserved proteins, which are essential for embryonic development. The key regulatory subunit, the bone morphogenetic protein 4 (BMP4), is overexpressed and associated with tumor metastasis in a variety of cancers. However, the prognostic and molecular features of gliomas with BMP4 expression is still unclear. METHODS: We obtained whole...
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