Article
Somatic CPEB4 and CPEB1 genes mutations spectrum on the prognostic predictive accuracy in patients with high-grade glioma and their clinical significance.
Journal of the neurological sciences - 15 Apr 2016
Boustani Mohammad Reza, Mehrabi Farzad, Yahaghi Emad, Khoshnood Reza Jalili, Shahmohammadi Mohammadreza, Darian Ebrahim Khodaveri, Goudarzi Peyman Karimi
Abstract excerpt
BACKGROUND: Glioblastoma (grade IV glioma/GBM) is characterized by extremely aggressive invasion and proliferative nature. OBJECTIVE: The main goal of this study was to evaluate the expression patterns of CPEB1 and CPEB4 in glioma patients. METHODS: 41 paraffin-embedded tissue samples with glioma (WHO I-IV) were collected between January 2008 and December 2012 in Tehran, Iran. MRI of patients was done before and...
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