A 4-Gene Signature Associated with Clinical Outcome in High-Grade Gliomas

Abstract excerpt

PURPOSE: Gene expression studies provide molecular insights improving the classification of patients with high-grade gliomas. We have developed a risk estimation strategy based on a combined analysis of gene expression data to search for robust biomarkers associated with outcome in these tumors. EXPERIMENTAL DESIGN: We performed a meta-analysis using 3 publicly available malignant gliomas microarray data sets...

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