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Article

Genome‐wide promoter methylation analysis identifies epigenetic silencing of <scp><i>MAPK</i></scp><i>13</i> in primary cutaneous melanoma

28 Mar 2013

Abstract excerpt

The involvement of epigenetic alterations in the pathogenesis of melanoma is increasingly recognized. Here, we performed genome-wide DNA methylation analysis of primary cutaneous melanoma and benign melanocytic nevus interrogating 14 495 genes using BeadChip technology. This genome-wide view of promoter methylation in primary cutaneous melanoma revealed an array of recurrent DNA methylation alterations with...

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Share to Cutaneous Melanoma Detection and Management
Share to Epigenetics and DNA Methylation
Share to Melanoma and MAPK Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23590314
DOI: 10.1111/pcmr.12096

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