Article
Clinical cancer genomic profiling.
Nature reviews. Genetics - 1 Aug 2021
Chakravarty Debyani, Solit David B
Abstract excerpt
Technological innovation and rapid reduction in sequencing costs have enabled the genomic profiling of hundreds of cancer-associated genes as a component of routine cancer care. Tumour genomic profiling can refine cancer subtype classification, identify which patients are most likely to benefit from systemic therapies and screen for germline variants that influence heritable cancer risk. Here, we discuss ongoing...
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