Article
A decision support framework for genomically informed investigational cancer therapy.
Journal of the National Cancer Institute - 1 Jul 2015
Meric-Bernstam Funda, Johnson Amber, Holla Vijaykumar, Bailey Ann Marie, Brusco Lauren, Chen Ken, Routbort Mark, Patel Keyur P, Zeng Jia, Kopetz Scott, Davies Michael A, Piha-Paul Sarina A, Hong David S, Eterovic Agda Karina, Tsimberidou Apostolia M, Broaddus Russell, Bernstam Elmer V, Shaw Kenna R, Mendelsohn John, Mills Gordon B
Abstract excerpt
Rapidly improving understanding of molecular oncology, emerging novel therapeutics, and increasingly available and affordable next-generation sequencing have created an opportunity for delivering genomically informed personalized cancer therapy. However, to implement genomically informed therapy requires that a clinician interpret the patient's molecular profile, including molecular characterization of the tumor...
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