Article
Activation of mammalian target of rapamycin (mTOR) in triple negative feline mammary carcinomas.
BMC veterinary research - 15 Apr 2013
Maniscalco Lorella, Millán Yolanda, Iussich Selina, Denina Mauro, Sánchez-Céspedes Raquel, Gattino Francesca, Biolatti Bartolomeo, Sasaki Nobuo, Nakagawa Takayuki, Di Renzo Maria Flavia, de Las Mulas Juana Martín, De Maria Raffaella
Abstract excerpt
BACKGROUND: Triple negative breast cancer (TNBC) in humans is defined by the absence of oestrogen receptor (ER), progesterone receptor (PR) and HER2 overexpression. Mammalian target of rapamycin (mTOR) is overexpressed in TNBC and it represents a potential target for the treatment of this aggressive tumour. Feline mammary carcinoma (FMC) is considered to be a model for hormone-independent human breast cancer....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
