Article
Androgen receptor and FOXA1 coexpression define a "luminal-AR" subtype of feline mammary carcinomas, spontaneous models of breast cancer.
BMC cancer - 30 Dec 2019
Dagher Elie, Royer Violette, Buchet Paul, Abadie Jérôme, Loussouarn Delphine, Campone Mario, Nguyen Frédérique
Abstract excerpt
BACKGROUND: Invasive mammary carcinomas that spontaneously develop in female cats are associated with high mortality, and resemble the most aggressive human breast cancers, especially triple-negative breast cancer (TNBC). Transcriptome studies showed that TNBCs are a heterogeneous group that includes a potentially hormone-dependent subtype named luminal-AR. Some authors proposed an immunohistochemical definition...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
