Immature B cells can pass through a VHDJH/germ line state in the Ig H chain gene rearrangements.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Immature B cells can pass through a VHDJH/germ line state in the Ig H chain gene rearrangements.

Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 1990

Oka Y, Sugiyama H, Tsukada S, Kishimoto S

Abstract excerpt

SPL2-1-2, an Ig- murine immature B cell line, was established by the infection of immature B cells with tsOS-59, a temperature-sensitive mutant of Abelson murine leukemia virus. Southern blot and DNA cloning and sequencing analysis showed that SPL2-1-2 had a nonproductive VHQ52.DSP2.JH3 and a ger...

Topics

Alleles
Amino Acid Sequence
Animals
B-Lymphocytes
Base Sequence
Blotting, Southern
Cell Differentiation
Cell Line
Cloning, Molecular
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Mice
Molecular Sequence Data
Restriction Mapping

Source

Open in PubMed

Identifiers

PMID: 2358678

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2358678-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics