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Article

Electron diffraction study of lipids in non-lesional stratum corneum of atopic eczema patients.

Biochimica et biophysica acta - 1 Aug 2013

Janssens M, Mulder A A, van Smeden J, Pilgram G S K, Wolterbeek R, Lavrijsen A P M, Koning R I, Koster A J, Bouwstra J A

Abstract excerpt

Skin barrier impairment is thought to be an important factor in the pathogenesis of atopic eczema (AE). The skin barrier is located in the stratum corneum (SC), consisting of corneocytes embedded in lipids. Ceramides, cholesterol and free fatty acids are the major lipid classes and are crucial for the skin barrier function, but their role in relation to AE is indistinct. Filaggrin is an epidermal barrier protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23583924
DOI: 10.1016/j.bbamem.2013.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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