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Article

Identification of the outer-inner dynein linker as a hub controller for axonemal dynein activities.

Current biology : CB - 22 Apr 2013

Oda Toshiyuki, Yagi Toshiki, Yanagisawa Haruaki, Kikkawa Masahide

Abstract excerpt

BACKGROUND: In flagella, the outer dynein arm (ODA) and inner dynein arm (IDA) play distinct roles in generating beating motion. However, functional communications between the two dyneins have not been investigated. RESULTS: Here, we demonstrated by cryo-electron microscopy and chemical crosslinking that intermediate chain 2 (IC2) of ODAs interacts with the dynein regulatory complex in the axoneme and constitutes...

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Identifiers

PMID: 23583547
DOI: 10.1016/j.cub.2013.03.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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