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Article

Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Oct 2013

Zago Wagner, Schroeter Sally, Guido Teresa, Khan Karen, Seubert Peter, Yednock Ted, Schenk Dale, Gregg Keith M, Games Dora, Bard Frédérique, Kinney Gene G

Abstract excerpt

BACKGROUND: Clinical studies of β-amyloid (Aβ) immunotherapy in Alzheimer's disease (AD) patients have demonstrated reduction of central Aβ plaque by positron emission tomography (PET) imaging and the appearance of amyloid-related imaging abnormalities (ARIA). To better understand the relationship between ARIA and the pathophysiology of AD, we undertook a series of studies in PDAPP mice evaluating vascular...

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PMID: 23583235
DOI: 10.1016/j.jalz.2012.11.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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