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Article

Azole resistance in Aspergillus fumigatus isolates from respiratory specimens in Lyon University Hospitals, France: prevalence and mechanisms involved.

International journal of antimicrobial agents - 1 Dec 2021

Simon Loïc, Déméautis Tanguy, Dupont Damien, Kramer Rolf, Garnier Héloïse, Durieu Isabelle, Sénéchal Agathe, Reix Philippe, Couraud Sébastien, Devouassoux Gilles, Lina Bruno, Rabodonirina Meja, Wallon Martine, Dannaoui Eric, Persat Florence, Menotti Jean

Abstract excerpt

Resistance of Aspergillus fumigatus to triazoles has been reported increasingly in Europe. As few data are available from Southern France, the objectives of this study were to assess the burden of A. fumigatus isolates with azole resistance from clinical specimens in Lyon, and explore the resistance mechanisms involved. In this retrospective cross-sectional study, 221 consecutive A. fumigatus isolates from...

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PMID: 34619334
DOI: 10.1016/j.ijantimicag.2021.106447

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